Brotchie, Jonathan M.: search on Z-Library

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1

A novel dopamine D3R agonist SK609 with norepinephrine transporter inhibition promotes improvement in cognitive task performance in rodent and non-human primate models of Parkinson's disease

Schneider, Jay S., Marshall, Courtney A., Keibel, Lauren, Snyder, Nathaniel W., Hill, Michael P., Brotchie, Jonathan M., Johnston, Tom H., Waterhouse, Barry D., Kortagere, Sandhya

Journal:

Experimental Neurology

Year:

2021

File:

PDF, 61 KB

2021

2

Pharmacokinetic/Pharmacodynamic Correlation Analysis of Amantadine for Levodopa-Induced Dyskinesia

Brigham, Elizabeth, Johnston, Tom, Brown, Carl, Holt, Jonathon, Fox, Susan, Hill, Michael, Howson, Patrick, Brotchie, Jonathan, Nguyen, Jack

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2018

Language:

english

File:

PDF, 494 KB

english, 2018

3

[Blue Books of Neurology] MOVEMENT DISORDERS 4 Volume 34 || Functional Anatomy and Pathophysiology of the Basal Ganglia

Brotchie, Jonathan M.

Year:

2010

Language:

english

File:

PDF, 280 KB

english, 2010

4

Beneficial effects of trehalose on striatal dopaminergic deficits in rodent and primate models of synucleinopathy in Parkinson's disease.

Howson, Patrick A., Johnston, Tom H., Ravenscroft, Paula, Hill, Michael P, Su, Jin, Brotchie, Jonathan M., Koprich, James B.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2019

Language:

english

File:

PDF, 617 KB

english, 2019

5

Presymptomatic compensation in Parkinson's disease is not dopamine-mediated

Erwan Bezard, Christian E. Gross, Jonathan M. Brotchie

Journal:

Trends in Neurosciences

Year:

2003

Language:

english

File:

PDF, 158 KB

english, 2003

6

Treatment with Trehalose Prevents Behavioral and Neurochemical Deficits Produced in an AAV α-Synuclein Rat Model of Parkinson’s Disease

He, Qing, Koprich, James B., Wang, Ying, Yu, Wen-bo, Xiao, Bao-guo, Brotchie, Jonathan M., Wang, Jian

Journal:

Molecular Neurobiology

Year:

2016

Language:

english

File:

PDF, 4.16 MB

english, 2016

7

Effect of Repeatedl-DOPA, Bromocriptine, or Lisuride Administration on Preproenkephalin-A and Preproenkephalin-B mRNA Levels in the Striatum of the 6-Hydroxydopamine-Lesioned Rat

Brian Henry, Alan R. Crossman, Jonathan M. Brotchie

Journal:

Experimental Neurology

Year:

1999

Language:

english

File:

PDF, 288 KB

english, 1999

8

Characterisation of striatal NMDA receptors involved in the generation of parkinsonian symptoms: Intrastriatal microinjection studies in the 6-OHDA-lesioned rat

Joanne E. Nash, Jonathan M. Brotchie

Journal:

Movement Disorders

Year:

2002

Language:

english

File:

PDF, 272 KB

english, 2002

9

The serotonergic system in Parkinson's disease

Philippe Huot, Susan H. Fox, Jonathan M. Brotchie

Journal:

Progress in Neurobiology

Year:

2011

Language:

english

File:

PDF, 2.49 MB

english, 2011

10

Pridopidine, a clinic-ready compound, reduces 3,4-dihydroxyphenylalanine-induced dyskinesia in Parkinsonian macaques

Johnston, Tom H., Geva, Michal, Steiner, Lilach, Orbach, Aric, Papapetropoulos, Spyros, Savola, Juha-Matti, Reynolds, Ian J., Ravenscroft, Paula, Hill, Michael, Fox, Susan H., Brotchie, Jonathan M., L

Journal:

Movement Disorders

Year:

2018

Language:

english

File:

PDF, 287 KB

english, 2018

11

The α2-adrenergic receptor antagonist idazoxan reduces dyskinesia and enhances anti-parkinsonian actions of L-dopa in the MPTP-lesioned primate model of Parkinson's disease

Brian Henry, Susan H. Fox, David Peggs, Alan R. Crossman, Jonathan M. Brotchie

Journal:

Movement Disorders

Year:

1999

Language:

english

File:

PDF, 152 KB

english, 1999

12

Functional interaction between adenosine A2A and group III metabotropic glutamate receptors to reduce parkinsonian symptoms in rats

Sebastien Lopez, Nathalie Turle-Lorenzo, Tom H. Johnston, Jonathan M. Brotchie, Stephan Schann, Pascal Neuville, Marianne Amalric

Journal:

Neuropharmacology

Year:

2008

Language:

english

File:

PDF, 583 KB

english, 2008

13

Novel nondopaminergic targets for motor features of Parkinson's disease: Review of recent trials

Kalia, Lorraine V., Brotchie, Jonathan M., Fox, Susan H.

Journal:

Movement Disorders

Year:

2013

Language:

english

File:

PDF, 1.50 MB

english, 2013

14

Use of catechol- O -methyltransferase inhibition to minimize L-3,4-dihydroxyphenylalanine-induced dyskinesia in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque

Huot, Philippe, Johnston, Tom H., Snoeren, Tessa, Koprich, James B., Hill, Michael P., Fox, Susan H., Brotchie, Jonathan M.

Journal:

European Journal of Neuroscience

Year:

2013

Language:

english

File:

PDF, 1.07 MB

english, 2013

15

Monoamine Reuptake Inhibitors in Parkinson’s Disease

Huot, Philippe, Fox, Susan H., Brotchie, Jonathan M.

Journal:

Parkinson's Disease

Year:

2015

Language:

english

File:

PDF, 295 KB

english, 2015

16

The highly-selective 5-HT1A agonist F15599 reduces l-DOPA-induced dyskinesia without compromising anti-parkinsonian benefits in the MPTP-lesioned macaque

Huot, Philippe, Johnston, Tom H., Fox, Susan H., Newman-Tancredi, Adrian, Brotchie, Jonathan M.

Journal:

Neuropharmacology

Year:

2015

Language:

english

File:

PDF, 781 KB

english, 2015

17

Early-onset impairment of the ubiquitin-proteasome system in dopaminergic neurons caused by Î±-synuclein

McKinnon, Chris, De Snoo, Mitchell L., Gondard, Elise, Neudorfer, Clemens, Chau, Hien, Ngana, Sophie G., OâHara, Darren M., Brotchie, Jonathan M., Koprich, James B., Lozano, Andres M., Kalia, Lorrai

Journal:

Acta Neuropathologica Communications

Year:

2020

File:

PDF, 6.52 MB

2020

18

Striatal histone modifications in models of levodopa-induced dyskinesia

Anthony P. Nicholas, Farah D. Lubin, Penelope J. Hallett, Padmapriya Vattem, Paula Ravenscroft, Erwan Bezard, Shaobo Zhou, Susan H. Fox, Jonathan M. Brotchie, J. David Sweatt, David G. Standaert

Journal:

Journal of Neurochemistry

Year:

2008

Language:

english

File:

PDF, 436 KB

english, 2008

19

Paradoxical action of the cannabinoid WIN 55,212-2 in stimulated and basal cyclic AMP accumulation in rat globus pallidus slices

Yannick P. Maneuf, Jonathan M. Brotchie

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 266 KB

english, 1997

20

Non-dopaminergic treatments in development for Parkinson's disease

Susan H Fox, Jonathan M Brotchie, Anthony E Lang

Journal:

The Lancet Neurology

Year:

2008

Language:

english

File:

PDF, 368 KB

english, 2008

21

Increased striatal pre-proenkephalin B expression is associated with dyskinesia in Parkinson’s disease

Brian Henry, Susan Duty, Susan H Fox, Alan R Crossman, Jonathan M Brotchie

Journal:

Experimental Neurology

Year:

2003

Language:

english

File:

PDF, 422 KB

english, 2003

22

L-745,870 reduces the expression of abnormal involuntary movements in the 6-OHDA-lesioned rat

Huot, Philippe, Johnston, Tom H., Koprich, James B., Espinosa, Maria C., Reyes, Maria Gabriela, Fox, Susan H., Brotchie, Jonathan M.

Journal:

Behavioural Pharmacology

Year:

2015

Language:

english

File:

PDF, 919 KB

english, 2015

23

Serotonin and Parkinson's disease: On movement, mood, and madness

Susan H. Fox, Rosalind Chuang, Jonathan M. Brotchie

Journal:

Movement Disorders

Year:

2009

Language:

english

File:

PDF, 122 KB

english, 2009

24

Increased levels of 5-HT1A receptor binding in ventral visual pathways in Parkinson's disease

Philippe Huot, Tom H. Johnston, Naomi P. Visanji, Tayyeba Darr, Donna Pires, Lili-Naz Hazrati, Jonathan M. Brotchie, Susan H. Fox

Journal:

Movement Disorders

Year:

2012

Language:

english

File:

PDF, 826 KB

english, 2012

25

Receptor-activity modifying protein 1 expression is increased in the striatum following repeated L-DOPA administration in a 6-hydroxydopamine lesioned rat model of Parkinson's disease

Joohyung Lee, Jordi Gomez-Ramirez, Tom H. Johnston, Naomi Visanji, Jonathan M. Brotchie

Journal:

Year:

2008

Language:

english

File:

PDF, 160 KB

english, 2008

26

[International Review of Neurobiology] Pathophysiology, Pharmacology, and Biochemistry of Dyskinesia Volume 98 || New Approaches to Therapy

Brotchie, Jonathan

Year:

2011

Language:

english

File:

PDF, 218 KB

english, 2011

27

Adjuncts to dopamine replacement: A pragmatic approach to reducing the problem of dyskinesia in Parkinson's disease

Dr. Jonathan M. Brotchie

Journal:

Movement Disorders

Year:

1998

Language:

english

File:

PDF, 735 KB

english, 1998

28

Changes in the mRNA Levels of α2Aand α2CAdrenergic Receptors in Rat Models of Parkinson’s Disease andl-DOPA-Induced Dyskinesia

Amal Alachkar, Jonathan M. Brotchie, Owen T. Jones

Journal:

Journal of Molecular Neuroscience

Year:

2012

Language:

english

File:

PDF, 296 KB

english, 2012

29

Dopamine D3 receptor stimulation underlies the development of L-DOPA-induced dyskinesia in animal models of Parkinson's disease

Naomi P. Visanji, Susan H. Fox, Tom Johnston, Gabriela Reyes, Mark J. Millan, Jonathan M. Brotchie

Journal:

Neurobiology of Disease

Year:

2009

Language:

english

File:

PDF, 925 KB

english, 2009

30

Actions at sites other than D3 receptors mediate the effects of BP897 on l-DOPA-induced hyperactivity in monoamine-depleted rats

Naomi P. Visanji, Mark J. Millan, Jonathan M. Brotchie

Journal:

Experimental Neurology

Year:

2006

Language:

english

File:

PDF, 262 KB

english, 2006

31

Reply to Can STN DBS protect both nigral somata and innervation of the striatum?

Koprich, James B, Brotchie, Jonathan M, Musacchio, Thomas, Volkmann, Jens, Ip, Chi Wang

Journal:

Annals of Neurology

Year:

2017

Language:

english

File:

PDF, 488 KB

english, 2017

32

Viewpoint: Developing drugs for levodopa-induced dyskinesia in PD: Lessons learnt, what does the future hold?

Fox, Susan H, Brotchie, Jonathan M

Journal:

European Journal of Neuroscience

Year:

2018

Language:

english

File:

PDF, 219 KB

english, 2018

33

Histamine H3 receptor agonists reduce L-dopa–induced chorea, but not dystonia, in the MPTP-lesioned nonhuman primate model of Parkinson's disease

Jordi Gomez-Ramirez, Tom H. Johnston, Naomi P. Visanji, Susan H. Fox, Jonathan M. Brotchie

Journal:

Movement Disorders

Year:

2006

Language:

english

File:

PDF, 184 KB

english, 2006

34

On the Role of Enkephalin Cotransmission in the GABAergic Striatal Efferents to the Globus Pallidus

Yannick P. Maneuf, Ian J. Mitchell, Alan R. Crossman, Jonathan M. Brotchie

Journal:

Experimental Neurology

Year:

1994

File:

PDF, 426 KB

1994

35

Upregulation of Striatal Preproenkephalin Gene Expression Occurs before the Appearance of Parkinsonian Signs in 1-Methyl-4-phenyl- 1,2,3,6-tetrahydropyridine Monkeys

Erwan Bezard, Paula Ravenscroft, Christian E. Gross, Alan R. Crossman, Jonathan M. Brotchie

Journal:

Neurobiology of Disease

Year:

2001

Language:

english

File:

PDF, 128 KB

english, 2001

36

Levodopa-Induced Dyskinesia in Parkinson's Disease || Features and Mechanisms of Diphasic Dyskinesia in Parkinson’s Disease

Fox, Susan H., Brotchie, Jonathan M.

Year:

2014

Language:

english

File:

PDF, 233 KB

english, 2014

37

Advances in the delivery of treatments for Parkinson’s disease

Johnston, Tom H, Fox, Susan H, Brotchie, Jonathan M

Journal:

Expert Opinion on Drug Delivery

Year:

2005

Language:

english

File:

PDF, 210 KB

english, 2005

38

Potential of Opioid Antagonists in the Treatment of Levodopa-Induced Dyskinesias in Parkinson’s Disease

Brian Henry,Jonathan M. Brotchie

Journal:

Year:

1996

Language:

english

File:

PDF, 1.41 MB

english, 1996

39

Antiparkinsonian effects of the novel D3/D2 dopamine receptor agonist, S32504, in MPTP-lesioned marmosets: Mediation by D2, not D3, dopamine receptors

Michael P. Hill, Paula Ravenscroft, Steven G. McGuire, Jonathan M. Brotchie, Alan R. Crossman, Catherine Rochat, Mark J. Millan

Journal:

Movement Disorders

Year:

2006

Language:

english

File:

PDF, 95 KB

english, 2006

40

Dihydropyridine calcium channel blockers and the progression of parkinsonism

Connie Marras, Andrea Gruneir, Paula Rochon, Xuesong Wang, Geoff Anderson, Jonathan Brotchie, Chaim M. Bell, Susan Fox, Peter C. Austin

Journal:

Annals of Neurology

Year:

2012

Language:

english

File:

PDF, 753 KB

english, 2012

41

Activation of the cannabinoid receptor by Δ9-tetrahydrocannabinol reduces γ-aminobutyric acid uptake in the globus pallidus

Yannick P. Maneuf, Joanne E. Nash, Alan R. Crossman, Jonathan M. Brotchie

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 306 KB

english, 1996

42

Ropinirole versus l-DOPA effects on striatal opioid peptide precursors in a rodent model of Parkinson's disease: implications for dyskinesia

Paula Ravenscroft, Sylvie Chalon, Jonathan M. Brotchie, Alan R. Crossman

Journal:

Experimental Neurology

Year:

2004

Language:

english

File:

PDF, 727 KB

english, 2004

43

New treatments for movement disorders?

Susan H. Fox, Jonathan M. Brotchie, S.H. Fox, J.M. Brotchie

Journal:

Trends in Pharmacological Sciences

Year:

1996

Language:

english

File:

PDF, 348 KB

english, 1996

44

Non-steric-zipper models for pathogenic α-synuclein conformers

Schuman, Brock, Won, Amy, Brand-Arzamendi, Koroboshka, Koprich, James B., Wen, Xiao-Yan, Howson, Patrick A., Brotchie, Jonathan M., Yip, Christopher M.

Journal:

APL Bioengineering

Year:

2018

Language:

english

File:

PDF, 5.64 MB

english, 2018

45

Progressive Neurodegeneration or Endogenous Compensation in an Animal Model of Parkinson's Disease Produced by Decreasing Doses of Alpha-Synuclein

Koprich, James B., Johnston, Tom H., Huot, Philippe, Reyes, M. Gabriela, Espinosa, Maria, Brotchie, Jonathan M., Dawson, Ted

Journal:

Year:

2011

Language:

english

File:

PDF, 601 KB

english, 2011

46

Fipamezole (JP-1730) is a potent α2 adrenergic receptor antagonist that reduces levodopa-induced dyskinesia in the MPTP-lesioned primate model of Parkinson's disease

Juha-Matti Savola, Michael Hill, Mia Engstrom, Hannele Merivuori, Siegfried Wurster, Steven G. McGuire, Susan H. Fox, Alan R. Crossman, Jonathan M. Brotchie

Journal:

Movement Disorders

Year:

2003

Language:

english

File:

PDF, 148 KB

english, 2003

47

Non-subtype-selective opioid receptor antagonism in treatment of levodopa-induced motor complications in Parkinson's disease

Susan Fox, Montague Silverdale, Mark Kellett, Rhys Davies, Malcolm Steiger, Nicholas Fletcher, Alan Crossman, Jonathan Brotchie

Journal:

Movement Disorders

Year:

2004

Language:

english

File:

PDF, 533 KB

english, 2004

48

Generation of a model of l-DOPA-induced dyskinesia in two different mouse strains

Sherri L. Thiele, Ruth Warre, Charline S. Khademullah, Nusrat Fahana, Charlotte Lo, Doris Lam, Sheena Talwar, Tom H. Johnston, Jonathan M. Brotchie, Joanne E. Nash

Journal:

Journal of Neuroscience Methods

Year:

2011

Language:

english

File:

PDF, 1.13 MB

english, 2011

49

Management of impulse control disorders in Parkinson's disease: Controversies and future approaches

Samuel, Michael, Rodriguez-Oroz, Maria, Antonini, Angelo, Brotchie, Jonathan M., Ray Chaudhuri, Kallol, Brown, Richard G., Galpern, Wendy R., Nirenberg, Melissa J., Okun, Michael S., Lang, Anthony E.

Journal:

Movement Disorders

Year:

2015

Language:

english

File:

PDF, 268 KB

english, 2015

50

Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson’s disease

DI MARZO, VINCENZO, HILL, MICHAEL P., BISOGNO, TIZIANA, CROSSMAN, ALAN R., BROTCHIE, JONATHAN M.

Journal:

The FASEB Journal

Year:

2000

Language:

english

File:

PDF, 229 KB

english, 2000

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